Office of Research Services and Genomics and Evolutionary Medicine (GEM) coordinated by Assist Prof. Dr. Thanat Chookajorn, Faculty of Tropical Medicine , co-hosted a Special talk titled
“Anitimalarial Lead Discovery: Exploiting phenotypic hits”
by Dr. Francisco Javier Gamo , Director of Malaria Discovery, GSK, Spain
On January 30, 2017 (15.00 -16.00 hr) at Pratap Singhasivanon Conference Room, 17th floor, Rajanakarindra Building, Faculty of Tropical Medicine, Mahidol University.
59 participants attended
Conclusion 1 (by Assist Prof. Dr. Thanat Chookajorn)
Dr. Francisco-Javier Gamo, the director of Malaria DPU at GSK, gave a presentation on “Anitimalarial Lead Discovery: Exploiting phenotypic hits”. He presented antimalarial drug development projects at GSK and discussed common challenges. For example, compounds that can kill parasites at low concentration in culture might not work in vivo. It is important to move quickly to in vivo testing in animal models. He also discussed latest approaches in drug development. One example presented at the seminar is to use microdosing in drug testing. Microdosing is a technique for studying pharmacokinetics in human by introducing low amount of a drug candidate into the system.